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64-channel multielectrode array (mea) recording system  (Alpha MED Scientific)


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    Alpha MED Scientific 64-channel multielectrode array (mea) recording system
    64 Channel Multielectrode Array (Mea) Recording System, supplied by Alpha MED Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/64-channel+multielectrode+recording+system/64+channel+multielectrode+system/bio_rxiv__2024__10__14__618205-236-1-7
    Average 90 stars, based on 1 article reviews
    64-channel multielectrode array (mea) recording system - by Bioz Stars, 2026-09
    90/100 stars

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    Article Title: Brain-derived neurotrophic factor produced long-term synaptic enhancement in the anterior cingulate cortex of adult mice.
    Article Snippet: In the present study, we aimed to study the effect of BDNF on synaptic transmission in ACC by using a 64-channel multielectrode (MED64) recording system.

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    Changed presynaptic transmitter release probably within aIC of observer and demonstrator mice. (A) Left: schematic diagram showing location of the <t>MED64</t> probe on the coronal IC slice; Right: light microscopy photograph showing relative location of aIC within the probe; (B) Spatial distribution of extracellular field potential induced by electrical stimulation on channel 45 (marked as red circle) in layers VI of aIC; (C,D) Input–output curve of fEPSP slope (%) vs. stimulus intensity (mA) in the slice among naïve ( n = 4 slices of 3 mice), observer ( n = 4 slices of 3 mice), and demonstrator ( n = 7 slices of 5 mice) in the superficial (C) and in the deep layers (D) of aIC; (E,F) Example traces of paired-pulse facilitation (PPF) with an interval of 25 ms recorded in the superficial (E) and deep layers (F) of aIC; (G,H) The paired-pulse ratios (slope of fEPSP2/slope of fEPSP1) recorded with intervals of 25, 50, 75, and 100 ms in superficial (G) and deep layers (H) of aIC; Data are shown as mean ± SEM (PPF: Naïve n = 4 slices of 3 mice, observer n = 7 slices of 6 mice, and demonstrator n = 4 slices of 4 mice) and compared by two-way ANOVA analysis followed by Tukey’s multiple comparisons test, * p < 0.05, vs. naïve.
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    Changed presynaptic transmitter release probably within aIC of observer and demonstrator mice. (A) Left: schematic diagram showing location of the <t>MED64</t> probe on the coronal IC slice; Right: light microscopy photograph showing relative location of aIC within the probe; (B) Spatial distribution of extracellular field potential induced by electrical stimulation on channel 45 (marked as red circle) in layers VI of aIC; (C,D) Input–output curve of fEPSP slope (%) vs. stimulus intensity (mA) in the slice among naïve ( n = 4 slices of 3 mice), observer ( n = 4 slices of 3 mice), and demonstrator ( n = 7 slices of 5 mice) in the superficial (C) and in the deep layers (D) of aIC; (E,F) Example traces of paired-pulse facilitation (PPF) with an interval of 25 ms recorded in the superficial (E) and deep layers (F) of aIC; (G,H) The paired-pulse ratios (slope of fEPSP2/slope of fEPSP1) recorded with intervals of 25, 50, 75, and 100 ms in superficial (G) and deep layers (H) of aIC; Data are shown as mean ± SEM (PPF: Naïve n = 4 slices of 3 mice, observer n = 7 slices of 6 mice, and demonstrator n = 4 slices of 4 mice) and compared by two-way ANOVA analysis followed by Tukey’s multiple comparisons test, * p < 0.05, vs. naïve.
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    Panasonic Healthcare 64 channel multielectrode array recording system med64 probe
    Changed presynaptic transmitter release probably within aIC of observer and demonstrator mice. (A) Left: schematic diagram showing location of the <t>MED64</t> probe on the coronal IC slice; Right: light microscopy photograph showing relative location of aIC within the probe; (B) Spatial distribution of extracellular field potential induced by electrical stimulation on channel 45 (marked as red circle) in layers VI of aIC; (C,D) Input–output curve of fEPSP slope (%) vs. stimulus intensity (mA) in the slice among naïve ( n = 4 slices of 3 mice), observer ( n = 4 slices of 3 mice), and demonstrator ( n = 7 slices of 5 mice) in the superficial (C) and in the deep layers (D) of aIC; (E,F) Example traces of paired-pulse facilitation (PPF) with an interval of 25 ms recorded in the superficial (E) and deep layers (F) of aIC; (G,H) The paired-pulse ratios (slope of fEPSP2/slope of fEPSP1) recorded with intervals of 25, 50, 75, and 100 ms in superficial (G) and deep layers (H) of aIC; Data are shown as mean ± SEM (PPF: Naïve n = 4 slices of 3 mice, observer n = 7 slices of 6 mice, and demonstrator n = 4 slices of 4 mice) and compared by two-way ANOVA analysis followed by Tukey’s multiple comparisons test, * p < 0.05, vs. naïve.
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    Changed presynaptic transmitter release probably within aIC of observer and demonstrator mice. (A) Left: schematic diagram showing location of the MED64 probe on the coronal IC slice; Right: light microscopy photograph showing relative location of aIC within the probe; (B) Spatial distribution of extracellular field potential induced by electrical stimulation on channel 45 (marked as red circle) in layers VI of aIC; (C,D) Input–output curve of fEPSP slope (%) vs. stimulus intensity (mA) in the slice among naïve ( n = 4 slices of 3 mice), observer ( n = 4 slices of 3 mice), and demonstrator ( n = 7 slices of 5 mice) in the superficial (C) and in the deep layers (D) of aIC; (E,F) Example traces of paired-pulse facilitation (PPF) with an interval of 25 ms recorded in the superficial (E) and deep layers (F) of aIC; (G,H) The paired-pulse ratios (slope of fEPSP2/slope of fEPSP1) recorded with intervals of 25, 50, 75, and 100 ms in superficial (G) and deep layers (H) of aIC; Data are shown as mean ± SEM (PPF: Naïve n = 4 slices of 3 mice, observer n = 7 slices of 6 mice, and demonstrator n = 4 slices of 4 mice) and compared by two-way ANOVA analysis followed by Tukey’s multiple comparisons test, * p < 0.05, vs. naïve.

    Journal: Frontiers in Synaptic Neuroscience

    Article Title: Different Synaptic Plasticity After Physiological and Psychological Stress in the Anterior Insular Cortex in an Observational Fear Mouse Model

    doi: 10.3389/fnsyn.2022.851015

    Figure Lengend Snippet: Changed presynaptic transmitter release probably within aIC of observer and demonstrator mice. (A) Left: schematic diagram showing location of the MED64 probe on the coronal IC slice; Right: light microscopy photograph showing relative location of aIC within the probe; (B) Spatial distribution of extracellular field potential induced by electrical stimulation on channel 45 (marked as red circle) in layers VI of aIC; (C,D) Input–output curve of fEPSP slope (%) vs. stimulus intensity (mA) in the slice among naïve ( n = 4 slices of 3 mice), observer ( n = 4 slices of 3 mice), and demonstrator ( n = 7 slices of 5 mice) in the superficial (C) and in the deep layers (D) of aIC; (E,F) Example traces of paired-pulse facilitation (PPF) with an interval of 25 ms recorded in the superficial (E) and deep layers (F) of aIC; (G,H) The paired-pulse ratios (slope of fEPSP2/slope of fEPSP1) recorded with intervals of 25, 50, 75, and 100 ms in superficial (G) and deep layers (H) of aIC; Data are shown as mean ± SEM (PPF: Naïve n = 4 slices of 3 mice, observer n = 7 slices of 6 mice, and demonstrator n = 4 slices of 4 mice) and compared by two-way ANOVA analysis followed by Tukey’s multiple comparisons test, * p < 0.05, vs. naïve.

    Article Snippet: The 64-channel multielectrode array recording system (MED64; Panasonic Alpha-Med Sciences, Osaka, Japan) was used for extracellular field potential recordings.

    Techniques: Light Microscopy